3860-OP

DTT

OmniPur^® Grade, >= 99.4%, Used for reduction of protein disulfide linkages

• Synonym(s): OmniPur^® DTT, Cleland′s Reagent, Dithiothreitol
• CAS Number: 3483-12-3
• MDL number: MFCD00004877
• UNSPSC Code: 12352209
• NACRES: NA.28

Properties

• grade: Molecular Biology
• Quality Level: 100
• Assay: ≥99.4%
• form: crystalline powder
• reaction suitability: reagent type: reductant
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: water: 5%
• foreign activity: DNAse, none detected; Protease, none detected; RNAse, none detected
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1
• InChI key: VHJLVAABSRFDPM-IMJSIDKUSA-N

Description

General description

Used for reduction of protein disulfide linkages. Molecular Biology

A (0.02 M in water): ≤0.05 AU
Assay (-SH content): ≥99.4%
DNAse: none detected
Infrared spectrum: Conforms to standard
Loss on drying: ≤0.5%
Melting point: 39-43°C
Protease: none detected
RNAse: none detected
Solubility (5%, water): To pass test





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Application

• Oxidative potential of particulate matter and its association to respiratory health endpoints in high-altitude cities in Bolivia.: This research investigates the oxidative potential of particulate matter and its impact on respiratory health in Bolivian high-altitude cities. DTT (Dithiothreitol) is used as a reducing agent to measure the oxidative potential of particulates, providing insights into their health impacts and guiding environmental policy (Borlaza-Lacoste et al., 2024).


• Protein purification via consecutive histidine-polyphosphate interaction.: This study explores an innovative method for protein purification using DTT to maintain reducing conditions essential for the preservation of protein structures. The findings highlight DTT′s role in enhancing the efficiency and yield of protein purification processes, which is critical for biochemical research and industrial applications (Zhou et al., 2024).

Warning

Toxicity: Harmful (C)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318
• Precautionary Statements: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable