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A1968

Sigma-Aldrich

Ascorbic acid 6-palmitate

meets USP testing specifications

Synonym(s):

6-O-Palmitoyl-L-ascorbic acid, L-Ascorbic acid 6-hexadecanoate, L-Ascorbyl palmitate, Ascorbic acid 6-palmitate, NSC 402451

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About This Item

Empirical Formula (Hill Notation):
C22H38O7
CAS Number:
137-66-6
Molecular Weight:
414.53
Beilstein:
96552
EC Number:
205-305-4
MDL number:
MFCD00005377
UNSPSC Code:
12352205
PubChem Substance ID:
24890608
NACRES:
NA.21

biological source

synthetic

Quality Level

200

Agency

USP/NF
meets USP testing specifications

Assay

95.0-100.5%

form

powder

color

light yellow

application(s)

pharmaceutical (small molecule)

SMILES string

CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O

InChI

1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1

InChI key

QAQJMLQRFWZOBN-LAUBAEHRSA-N

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General description

Ascorbic acid 6-palmitate/L-Ascorbyl 6-palmitate (AP) is a derivative of a synthetic lipophilic ascorbic acid.

Biochem/physiol Actions

L-Ascorbyl 6-palmitate (AP) is used as preservative in foods. In mice, AP works as a dietary antitumor promoter. 

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000333550
0000301672
0000349143
0000349146
0000349144

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A comparison of L-ascorbic acid and L-ascorbyl 6-palmitate utilization in Guinea Pigs and humans
Johnston CS, et al.
Nutrition Research (New York, N.Y.), 14(10), 1465-1471 (1994)
Gopa Mitra et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 149(4), 341-350 (2008-03-11)
The effect of supplementation of ascorbic acid through enriched zooplankton [10%, 20% and 30% ascorbyl palmitate (AP) inclusion in diet of zooplankton] on different digestive enzyme activities during ontogeny of Labeo rohita larvae was studied from 4 day to 15
Charlotte Jacobsen
Annals of the New York Academy of Sciences, 1190, 141-150 (2010-04-15)
Enrichment of foods with marine omega-3 polyunsaturated fatty acids (PUFA) poses a multidisciplinary challenge to food industry and academia. Although our knowledge about possible health effects of omega-3 PUFA has increased tremendously during the last 30 years, there is still
Luciano Benedini et al.
Colloids and surfaces. B, Biointerfaces, 89, 265-270 (2011-10-15)
Ascorbyl palmitate (Asc16) in polyethyleneglycol 400 (PEG 400)-water mixtures at weight fractions (w/w) between 0.05 and 1.0 were studied by differential scanning calorimetry (DSC) and polarizing microscopy (PM) at different temperatures. The employed PEG 400-water proportions were: 0-25-50% and 75%
P O Nnamani et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(1), 68-74 (2010-06-18)
P90Gylation refers to the modification of lipid molecules by one or more phospholipid chains. Phospholipon 90G (P90G) contains about 94.0% of phosphatidylcholine stabilized with 0.1% ascorbyl palmitate and is a safe (GRAS) FDA-approved parenteral excipient with wide applications in drug
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