ABC963

Anti-phospho Mitofusin2 Antibody (Ser442)

• Synonym(s): Mitofusin-2|Transmembrane GTPase MFN2
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 300
• clone: polyclonal
• species reactivity: human
• technique(s): inhibition assay: suitable (peptide); western blot: suitable

Description

General description

Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.

Immunogen

KLH-conjugated linear peptide corresponding to human phospho Mitofusin2 (Ser442).

Application

Anti-phospho Mitofusin2 Antibody (Ser442) is an antibody against phospho Mitofusin2 (Ser442) for use in Western Blotting, Peptide Inhibition Assay.

Quality

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 1.0 ug/mL of this antibody detected phospho Mitofusin2 (Ser442) in 10 ug of SH-SY5Y cell lysate.

Other Notes

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1