O2751

Sodium oxamate

≥98%

• Synonym(s): Aminooxoacetic acid sodium salt, Oxalic acid monoamide sodium salt, Oxamic acid sodium salt
• Linear Formula: NH₂COCOONa
• CAS Number: 565-73-1
• Molecular Weight: 111.03
• Beilstein: 6538153
• EC Number: 209-290-5
• MDL number: MFCD00044553
• UNSPSC Code: 12352202
• PubChem Substance ID: 24278607
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Assay: ≥98%
• form: powder
• mp: 300 °C
• solubility: water: 50 mg/mL, clear, colorless
• SMILES string: [Na+].NC(=O)C([O-])=O
• InChI: 1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
• InChI key: RQVZIJIQDCGIKI-UHFFFAOYSA-M

Description

Application

Sodium oxamate has been used:

• as one of the variable in flow injection analysis
• in in vitro angiogenesis assay
• to confirm the stimulatory role of stearic acid on lactate dehydrogenase mediated lactate production

Biochem/physiol Actions

Sodium oxamate influences the fatty acid metabolism. It might be useful for the treatment of diabetes.

Structural analog of pyruvate, inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway. Binding studies with lactate dehydrogenase; Mechanism of inhibition of mitochondrial pyruvate metabolism

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves