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Key Documents

D6875

Sigma-Aldrich

21-Hydroxyprogesterone

≥97% (HPLC)

Synonym(s):

11-Deoxycorticosterone, 11-Desoxycorticosterone, 21-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-21-ol-3,20-dione, Cortexone, DOC, Desoxycortone, Kendall’s desoxy compound B, ‘Reichstein Q’

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About This Item

Empirical Formula (Hill Notation):
C21H30O3
CAS Number:
Molecular Weight:
330.46
Beilstein:
2062123
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

sterility

non-sterile

Assay

≥97% (HPLC)

form

powder

solubility

ethanol: 50 mg/mL, clear, colorless to very faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CO

InChI

1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

InChI key

ZESRJSPZRDMNHY-YFWFAHHUSA-N

Gene Information

human ... SERPINA6(866)

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Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Carc. 2 - STOT RE 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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The faithful shutdown of the somatic program occurs in the early stage of reprogramming. Here, we examined the effect of in vivo reprogramming on Kras-induced cancer development. We show that the transient expression of reprogramming factors (1-3 days) in pancreatic
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J E Araújo et al.
The Science of the total environment, 687, 839-848 (2019-08-16)
The adverse effects of air pollution have been long studied in the lung and respiratory systems, but the molecular changes that this causes at the central nervous system level have yet to be fully investigated and understood. To explore the
Francesca Zalfa et al.
Cell death & disease, 8(11), e3169-e3169 (2017-11-17)
The fragile X mental retardation protein (FMRP) is lacking or mutated in patients with the fragile X syndrome (FXS), the most frequent form of inherited intellectual disability. FMRP affects metastasis formation in a mouse model for breast cancer. Here we
Xinliu Li et al.
Molecular microbiology, 103(4), 635-656 (2016-11-22)
Current treatment efforts for fungal infections are hampered by the limited availability of antifungal drugs and by the emergence of drug resistance. A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90. Hsp90

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