Stereospecific and highly stereoselective cyclopropanation reactions promoted by samarium.

Stereospecific and highly stereoselective cyclopropanation reactions promoted by samarium.

Chemical Society reviews (2010-08-05)

José M Concellón, Humberto Rodríguez-Solla, Carmen Concellón, Vicente del Amo

PMID20683534

ABSTRACT

Samarium metal and samarium diiodide have become important tools as selective cyclopropanating agents in organic synthesis due to their high chemo- and stereoselectivity. Therefore, Sm and SmI(2) are the ideal reagents to prepare cyclopropane derivatives. This tutorial review highlights C-C multiple bond cyclopropanation processes promoted by samarium or samarium diiodide.

MATERIALS

Product Number

Brand

Product Description

261203

Sigma-Aldrich

Samarium, −40 mesh, 99% trace rare earth metals basis

GF52166943

Samarium, foil, not light tested, 25x25mm, thickness 0.005mm, as rolled, 99%

GF75301668

Samarium, foil, not light tested, 50x50mm, thickness 0.025mm, as rolled, 99%

GF21658642

Samarium, foil, not light tested, 25x25mm, thickness 0.025mm, as rolled, 99%

GF98883848

Samarium, rod, 100mm, diameter 6.35mm, cast, 99%

GF55991076

Samarium, rod, 50mm, diameter 6.35mm, cast, 99%