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Key Documents

RAB0090

Sigma-Aldrich

Human CEACAM-1 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 20.58-15000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CEACAM1(634)

General description

The Human CEACAM-1 (Carcinoembryonic Antigen- related Cell Adhesion Molecule 1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CEACAM-1 in serum, plasma, cell culture supernatants and urine.
Serum carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a transmembrane glycoprotein and is localized to endothelial, epithelial, lymphoid and myeloid cells.The CEACAM-1 gene is mapped to human chromosome 19q13.2.

Immunogen

Recombinant Human CEACAM1

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Serum carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) participates in cell adhesion mechanism through homophilic or heterophilic interactions. Abnormal expression of the CEACAM1 gene is observed in a number of tumors. Ceacam1 possesses tyrosine phosphatase, an inhibitory motif, via which the receptor activates its inhibitory signals.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells.
Ashkenazi S, et al.
Oncotarget, 7(21), 30166-30166 (2016)
Rong Zhang et al.
Journal of ethnopharmacology, 155(1), 104-112 (2014-05-03)
The present study systematically investigate the in vivo and in vitro effect of total lignans (TL) extracted from Eucommia ulmoides Oliv. barks on bone formation using ovariectomy rat model and primary cultures of rat osteoblasts. Eighty 3-month-old female Sprague-Dawley rats
The HCMV-specific UL1 gene encodes a late phase glycoprotein incorporated in the virion envelope.
Shikhagaie M, et al.
Journal of Virology (2012)
CEACAM1: contact-dependent control of immunity.
Gray-Owen S D and Blumberg R S
Nature Reviews: Immunology, 6(6), 433-433 (2006)
Suppression of human metapneumovirus (HMPV) infection by the innate sensing gene CEACAM1.
Diab M, et al.
Oncotarget, 7(41), 66468-66468 (2016)
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