F7131

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

chromogenic, ≥99% (HPLC)

• Synonym(s): FAPGG, N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine
• Empirical Formula (Hill Notation): C₂₀H₂₁N₃O₆
• CAS Number: 64967-39-1
• Molecular Weight: 399.40
• MDL number: MFCD00036816
• UNSPSC Code: 12352202
• PubChem Substance ID: 24894929
• NACRES: NA.32

Properties

• product name: N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly,
• storage temp.: −20°C
• SMILES string: OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2
• InChI: 1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1
• InChI key: ZDLZKMDMBBMJLI-FDMDGMSGSA-N
• Gene Information: human ... ACE(1636) , ACE2(59272) ; mouse ... ACE3(217246) ; rat ... ACE(11421) , ACE2(70008) , ACE3(498012)

Description

Amino Acid Sequence

FA-Phe-Gly-Gly

General description

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly acts as a substrate for angiotensin converting enzyme (ACE), and is used in inhibitory assays of ACE.

Application

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly has been used for kinetic spectrophotometric assay of ACE (angiotensin converting enzyme) inhibitory activity.

Substrates

A substrate for continuous spectrophotometric assay of angiotensin converting enzyme (ACE).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves