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Key Documents

F2543

Sigma-Aldrich

D-(−)-Fructose

≥99% (HPLC), BioXtra

Synonym(s):

D-Levulose, Fruit sugar

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1239004
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

corn

product line

BioXtra

Assay

≥99% (HPLC)

form

powder

technique(s)

HPLC: suitable

impurities

<0.0005% Phosphorus (P)
<0.05% glucose (enzymatic)
<0.1% Insoluble matter

ign. residue

<0.1%

color

colorless

useful pH range

5.0-7.0 (25 °C, 18 g/L)

mp

119-122 °C (dec.) (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.005%
Pb: <0.001%
Zn: <0.0005%

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1

InChI key

BJHIKXHVCXFQLS-UYFOZJQFSA-N

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General description

D-(−)-Fructose is a C6-sugar.

Application

<ul>
<li><strong>Intracellular metabolomics and microRNAomics unveil new insight into the regulatory network for potential biocontrol mechanism of stress-tolerant Tricho-fusants interacting with phytopathogen Sclerotium rolfsii Sacc.</strong>: Explores the intracellular metabolomic and microRNAomic responses in Tricho-fusants, with D-(-)-Fructose identified as a key metabolite in stress tolerance and biocontrol mechanisms (Hirpara Gajera, 2023).</li>
<li><strong>Enzyme-based amperometric biosensors: 60 years later … Quo Vadis </strong>: Reviews advancements in enzyme-based biosensors over the past six decades, including the use of D-(-)-Fructose in the development of new biosensing technologies for clinical and environmental applications (Bollella, 2022).</li>
</ul>

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dehydration of D-fructose to hydroxymethylfurfural in sub-and supercritical fluids.
Bicker M, et al.
Journal of Supercritical Fluids, 36(2), 118-126 (2005)
K Takeshita et al.
Journal of bioscience and bioengineering, 90(4), 453-455 (2005-10-20)
An improved process for the mass production of D-psicose from D-fructose was developed. A D-fructose solution (60%, pH 7.0) was passed at 45 degrees C through a column filled with immobilized D-tagatose 3-epimerase (D-TE) which was produced using recombinant Escherichia
Combined dehydration/(transfer)-hydrogenation of C6-sugars (D-glucose and D-fructose) to ?-valerolactone using ruthenium catalysts.
Heeres H, et al.
Green Chemistry, 11(8), 1247-1255 (2009)
Hamza Landari et al.
Micromachines, 9(10) (2018-11-15)
In this paper, we present a new FTIR-based microfluidic system for Glucose, Fructose and Sucrose detection. The proposed microfluidic system is based on a pseudo-continuous flow coupled to a microscope-FTIR instrument. The detection and characterization of sugar samples were performed
Xiaobo Wang et al.
Cell metabolism, 31(5), 969-986 (2020-04-08)
Incomplete understanding of how hepatosteatosis transitions to fibrotic non-alcoholic steatohepatitis (NASH) has limited therapeutic options. Two molecules that are elevated in hepatocytes in human NASH liver are cholesterol, whose mechanistic link to NASH remains incompletely understood, and TAZ, a transcriptional

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