28266

Levofloxacin

98.0-102.0% anhydrous basis (HPLC)

• Synonym(s): Levofloxacin Anhydrous, (−)-Ofloxacin
• Empirical Formula (Hill Notation): C₁₈H₂₀FN₃O₄
• CAS Number: 100986-85-4
• Molecular Weight: 361.37
• UNSPSC Code: 51102829
• NACRES: NA.85
• PubChem Substance ID: 57648297
• MDL number: MFCD00865049
• Beilstein/REAXYS Number: 7327015

Properties

• biological source: synthetic
• Quality Segment: 200
• assay: 98.0-102.0% anhydrous basis (HPLC)
• form: powder or crystals
• color: light yellow-white to yellow-white
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: enzyme | inhibits
• SMILES string: OC(C(C1=O)=CN2C(C1=CC(F)=C3N4CCN(C)CC4)=C3OC[C@@H]2C)=O
• InChI: 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
• InChI key: GSDSWSVVBLHKDQ-JTQLQIEISA-N
• Gene Information: human ... KCNH1(3756)

Description

Application

Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Antibiotic against bacterial respiratory tract infections.

Biochem/physiol Actions

Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, thereby inhibiting cell division.

Packaging

10mg, 1g, 10g

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H317,H334
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1A - Skin Sens. 1A
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves