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  • Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.

Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.

Chemical communications (Cambridge, England) (2006-05-31)
Steven J Moss, Isabelle Carletti, Carlos Olano, Rose M Sheridan, Michael Ward, Vidya Math, Mohammad Nur-E-Alam, Alfredo F Braña, Ming Qiang Zhang, Peter F Leadlay, Carmen Méndez, José A Salas, Barrie Wilkinson
PMID16733573
ABSTRACT

We report the directed biosynthesis of borrelidin analogues and their selective anti-proliferative activity against human cancer cell lines.