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Synthesis of N-alkoxyphthalimides under ultrasound irradiation.

Ultrasonics sonochemistry (2007-09-04)
Shu-Xiang Wang, Xin-Wei Li, Ji-Tai Li
ABSTRACT

The alkylation of N-hydroxyphthalimide with alkyl halides in the presence of potassium carbonate results N-alkoxyphthalimides in 64-99% yields in DMSO under ultrasound irradiation. Compared with conventional methods, the main advantages of the present procedure are milder conditions, shorter reaction time and higher yields.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2-Bromoacetophenone, 98%
Supelco
2-Bromoacetophenone, for GC derivatization, LiChropur, ≥99.0%