- The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells.
The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells.
PloS one (2019-05-21)
Joana Sales-Dias, Gabriela Silva, Márcia Lamy, Andreia Ferreira, Ana Barbas
PMID31107884
ABSTRACT
These findings provide further evidence that DLL1 exerts carcinogenic effects in BC cells. The dissimilar effects of DLL1 downregulation observed amongst MCF-7, BT474, and MDA-MB-231 cells is likely due to their distinctive genetic and biologic characteristics, suggesting that DLL1 contributes to BC through various mechanisms.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Anti-α-Tubulin antibody, Mouse monoclonal, clone DM1A, purified from hybridoma cell culture