UBB
ubiquitin B
Synonyms:
Species:
Human UBB (7314), Mouse Ubb (22187), Rat Ubb (192255), Zebrafish ubb (550134), chicken UBB (396190), dog UBB (479513), domestic cat UBB (101091319), Horse UBB (100049794), cow UBB (281370), naked mole-rat Ubb (101702552)
UniProtKB ID:
Gene ID:
- Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
- Mouse(22187) ubiquitin B
- Rat(192255) ubiquitin B
- Zebrafish(550134) ubiquitin B
- chicken(396190) ubiquitin B
- dog(479513) ubiquitin B
- domestic cat(101091319) ubiquitin B
- Horse(100049794) ubiquitin B
- cow(281370) ubiquitin B
- naked mole-rat(101702552) ubiquitin B
- domestic guinea pig(100722422) ubiquitin B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Ubiquitin Antibody, clone 5Y8J0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-UBB antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Ubiquitin Antibody, clone 5J3V7, Rabbit Monoclonal, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Ubiquitin Lys63 Antibody, clone HWA4C4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Anti-phospho-Ubiquitin (Ser57), ,
Species Reactivity
chimpanzee, hamster, human, mouse, rat
Application
affinity binding assay
western blot
western blot