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Merck

SPTBN1

spectrin, beta, non-erythrocytic 1

Synonyms:
ELF, SPTB2, betaSpII
Species:
UniProtKB ID:
Gene ID:
  • Human(6711) Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20742) spectrin beta, non-erythrocytic 1
  • Rat(305614) spectrin, beta, non-erythrocytic 1
  • cow(526027) spectrin, beta, non-erythrocytic 1
  • Horse(100052695) spectrin, beta, non-erythrocytic 1
  • domestic cat(101090509) spectrin, beta, non-erythrocytic 1
  • naked mole-rat(101714374) spectrin, beta, non-erythrocytic 1
  • domestic guinea pig(100712783) spectrin, beta, non-erythrocytic 1
  • dog(403743) spectrin, beta, non-erythrocytic 1
  • chicken(421216) spectrin, beta, non-erythrocytic 1
  • Zebrafish(100316998) spectrin, beta, non-erythrocytic 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SPTBN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SPTBN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Spectrin beta-II Antibody, clone 2A7, clone 2A7, from mouse,
Species Reactivity
human, rabbit
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Beta-IV spectrin Antibody, clone N393/76, clone N393/76, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPTBN1,
Species
human