HDAC8
histone deacetylase 8
Synonyms:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
Species:
Human HDAC8 (55869), Mouse Hdac8 (70315), Rat Hdac8 (363481), domestic guinea pig Hdac8 (100721893), chicken HDAC8 (422182), Zebrafish hdac8 (406740), domestic cat HDAC8 (101096383), dog HDAC8 (480957), sheep HDAC8 (101110121), cow HDAC8 (540666)
UniProtKB ID:
Gene ID:
- Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(70315) histone deacetylase 8
- Rat(363481) histone deacetylase 8
- domestic guinea pig(100721893) histone deacetylase 8
- chicken(422182) histone deacetylase 8
- Zebrafish(406740) histone deacetylase 8
- domestic cat(101096383) histone deacetylase 8
- dog(480957) histone deacetylase 8
- sheep(101110121) histone deacetylase 8
- cow(540666) histone deacetylase 8
- naked mole-rat(101697998) histone deacetylase 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
[KO Validated]Anti-HDAC8 Antibody, clone 1O2Y5, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HDAC8 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HDAC8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
HDAC-8 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Species
human