GFI1
growth factor independent 1 transcription repressor
Synonyms:
GFI-1, GFI1A, SCN2, ZNF163
Species:
Human GFI1 (2672), Mouse Gfi1 (14581), Rat Gfi1 (24388), domestic guinea pig Gfi1 (100716876), naked mole-rat Gfi1 (101715410), dog GFI1 (490156), domestic cat GFI1 (100127020), cow GFI1 (100139952), sheep GFI1 (101116880), chicken GFI1 (429088)
UniProtKB ID:
Gene ID:
- Human(2672) Summary: This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14581) growth factor independent 1
- Rat(24388) growth factor independent 1 transcription repressor
- domestic guinea pig(100716876) growth factor independent 1 transcription repressor
- naked mole-rat(101715410) growth factor independent 1 transcription repressor
- dog(490156) growth factor independent 1 transcription repressor
- domestic cat(100127020) growth factor independent 1 transcription repressor
- cow(100139952) growth factor independent 1 transcription repressor
- sheep(101116880) growth factor independent 1 transcription repressor
- chicken(429088) growth factor independent 1 transcription repressor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GFI1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, pig, rat
Application
western blot
Monoclonal Anti-GFI1 antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species