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Merck

GAMT

guanidinoacetate N-methyltransferase

Synonyms:
CCDS2, PIG2, TP53I2
Species:
UniProtKB ID:
Gene ID:
  • Human(2593) Summary: The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. [provided by RefSeq, Feb 2012]
  • Mouse(14431) guanidinoacetate methyltransferase
  • Rat(25257) guanidinoacetate N-methyltransferase
  • naked mole-rat(101701700) guanidinoacetate N-methyltransferase
  • domestic guinea pig(100735222) guanidinoacetate N-methyltransferase
  • Zebrafish(796865) guanidinoacetate N-methyltransferase
  • chicken(770737) guanidinoacetate N-methyltransferase
  • dog(485085) guanidinoacetate N-methyltransferase
  • domestic cat(101096703) guanidinoacetate N-methyltransferase
  • cow(515270) guanidinoacetate N-methyltransferase

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GAMT, (C-terminal) antibody produced in mouse, clone 3H4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-GAMT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GAMT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GAMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GAMT,
Species
human