F2RL1
coagulation factor II (thrombin) receptor-like 1
GPR11, PAR2
Human F2RL1 (2150), Mouse F2rl1 (14063), Rat F2rl1 (116677), sheep F2RL1 (101106266), dog F2RL1 (488940), domestic cat F2RL1 (101082879), cow F2RL1 (526525), naked mole-rat F2rl1 (101708898), domestic guinea pig F2rl1 (100719602), chicken F2RL1 (427213)
- Human(2150) Summary: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]
- Mouse(14063) coagulation factor II (thrombin) receptor-like 1
- Rat(116677) coagulation factor II (thrombin) receptor-like 1
- sheep(101106266) coagulation factor II (thrombin) receptor-like 1
- dog(488940) coagulation factor II (thrombin) receptor-like 1
- domestic cat(101082879) coagulation factor II (thrombin) receptor-like 1
- cow(526525) coagulation factor II (thrombin) receptor-like 1
- naked mole-rat(101708898) coagulation factor II (thrombin) receptor-like 1
- domestic guinea pig(100719602) coagulation factor II (thrombin) receptor-like 1
- chicken(427213) coagulation factor II (thrombin) receptor-like 1
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