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Merck

DIABLO

diablo, IAP-binding mitochondrial protein

Synonyms:
DFNA64, SMAC
Species:
UniProtKB ID:
Gene ID:
  • Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Mouse(66593) diablo homolog (Drosophila)
  • Rat(288753) diablo, IAP-binding mitochondrial protein
  • chicken(416860) diablo, IAP-binding mitochondrial protein
  • cow(493999) diablo, IAP-binding mitochondrial protein
  • domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
  • naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
  • sheep(101121971) diablo, IAP-binding mitochondrial protein
  • dog(477463) diablo, IAP-binding mitochondrial protein

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ELISA

Product Number
Description
Species
Rat DIABLO / Diablo Homolog (Drosophila) ELISA Kit, ,
Species
rat
Mouse Diablo / Diablo Homolog, Mitochondrial ELISA Kit, ,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Smac antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-SMAC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Smac/Diablo antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-DIABLO antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-DIABLO antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DIABLO, RP11-512M8.5,
Species
human
MISSION® esiRNA, targeting mouse Diablo,
Species
mouse