CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Synonyms:
INK4D, p19, p19-INK4D
Species:
Human CDKN2D (1032), Mouse Cdkn2d (12581), Rat Cdkn2d (494444), domestic guinea pig Cdkn2d (100717134), dog CDKN2D (611216), naked mole-rat Cdkn2d (101720531), domestic cat CDKN2D (101091765), cow CDKN2D (510244), sheep CDKN2D (101118528)
UniProtKB ID:
Gene ID:
- Human(1032) Summary: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
- Mouse(12581) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- Rat(494444) similar to cyclin-dependent kinase inhibitor 2D
- domestic guinea pig(100717134) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- dog(611216) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- naked mole-rat(101720531) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- domestic cat(101091765) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- cow(510244) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
- sheep(101118528) cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CDKN2D antibody produced in mouse, clone 2E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CDKN2D antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
p19INK4D, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human