ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
Synonyms:
ATP1A1, ATP1AL2
Species:
Human ATP1A4 (480), Mouse Atp1a4 (27222), Rat Atp1a4 (29132), domestic guinea pig Atp1a4 (100729796), Horse ATP1A4 (100058301), sheep ATP1A4 (101118398), naked mole-rat Atp1a4 (101721060), dog ATP1A4 (488637), domestic cat ATP1A4 (101096375), cow ATP1A4 (537960)
UniProtKB ID:
Gene ID:
- Human(480) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(27222) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- Rat(29132) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- domestic guinea pig(100729796) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- Horse(100058301) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- sheep(101118398) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- naked mole-rat(101721060) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- dog(488637) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- domestic cat(101096375) ATPase, Na+/K+ transporting, alpha 4 polypeptide
- cow(537960) ATPase, Na+/K+ transporting, alpha 4 polypeptide
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Small Molecule - Inhibitor
Product Number
Description
Species
Digoxin, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human