ASB7
ankyrin repeat and SOCS box containing 7
Human ASB7 (140460), Mouse Asb7 (117589), Rat Asb7 (365277), domestic guinea pig Asb7 (100713127), naked mole-rat Asb7 (101701640), sheep ASB7 (101115908), Domestic Rabbit ASB7 (100359252), cow ASB7 (507483), Horse ASB7 (100050201), domestic cat ASB7 (101099556) ...More
- Human(140460) Summary: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(117589) ankyrin repeat and SOCS box-containing 7
- Rat(365277) ankyrin repeat and SOCS box-containing 7
- domestic guinea pig(100713127) ankyrin repeat and SOCS box containing 7
- naked mole-rat(101701640) ankyrin repeat and SOCS box containing 7
- sheep(101115908) ankyrin repeat and SOCS box containing 7
- Domestic Rabbit(100359252) ankyrin repeat and SOCS box containing 7
- cow(507483) ankyrin repeat and SOCS box containing 7
- Horse(100050201) ankyrin repeat and SOCS box containing 7
- domestic cat(101099556) ankyrin repeat and SOCS box containing 7
- Zebrafish(405798) ankyrin repeat and SOCS box-containing 7
- chicken(415518) ankyrin repeat and SOCS box containing 7
- dog(488707) ankyrin repeat and SOCS box containing 7
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