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  • Palladium-catalyzed cross-coupling of 3-iodobut-3-enoic acid with organometallic reagents. Synthesis Of 3-substituted but-3-enoic acids

Palladium-catalyzed cross-coupling of 3-iodobut-3-enoic acid with organometallic reagents. Synthesis Of 3-substituted but-3-enoic acids

The Journal of organic chemistry (2000-11-15)
Abarbri, Parrain, Kitamura, Noyori, Duchene
RESUMEN

3-Substituted but-3-enoic acids were obtained in good yields under mild experimental conditions by palladium-catalyzed cross-coupling of 3-iodobut-3-enoic acid with organozinc or organotin compounds using PdCl(2)(MeCN)(2) as catalyst and DMF as solvent.

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Sigma-Aldrich
Bis(acetonitrile)dichloropalladium(II), 99%