- Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature.
Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature.
The Journal of cell biology (2017-09-20)
Frederic Daste, Astrid Walrant, Mikkel R Holst, Jonathan R Gadsby, Julia Mason, Ji-Eun Lee, Daniel Brook, Marcel Mettlen, Elin Larsson, Steven F Lee, Richard Lundmark, Jennifer L Gallop
PMID28923975
RESUMEN
The conditional use of actin during clathrin-mediated endocytosis in mammalian cells suggests that the cell controls whether and how actin is used. Using a combination of biochemical reconstitution and mammalian cell culture, we elucidate a mechanism by which the coincidence of PI(4,5)P