Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.

Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.

Bioorganic & medicinal chemistry letters (2007-07-10)

Michael A Letavic, Emily M Stocking, Ann J Barbier, Pascal Bonaventure, Jamin D Boggs, Brian Lord, Kirsten L Miller, Sandy J Wilson, Nicholas I Carruthers

PMID17616397

RESUMEN

The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described.