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Merck

Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (1999-10-29)
G M Williams, M J Iatropoulos, J Whysner
RESUMEN

Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) are widely used antioxidant food additives. They have been extensively studied for potential toxicities. This review details experimental studies of genotoxicity and carcinogenicity which bear on cancer hazard assessment of exposure to humans. We conclude that BHA and BHT pose no cancer hazard and, to the contrary, may be anticarcinogenic at current levels of food additive use.

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Sigma-Aldrich
2,6-Di-tert-butyl-4-methylphenol, ≥99%, FCC, FG
Sigma-Aldrich
Butylated hydroxyanisole, ≥98.5%
USP
2,6-Di-tert-butyl-4-methylphenol, United States Pharmacopeia (USP) Reference Standard
Supelco
2,6-Di-tert-butyl-4-methylphenol, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Butylated hydroxyanisole, 99%, FCC, FG
Supelco
3,5-Di-tert-4butylhydroxytoluene (BHT), analytical standard
Sigma-Aldrich
2,6-Di-tert-butyl-4-methylphenol, purum, ≥99.0% (GC)
Supelco
Butylated hydroxyanisole, Pharmaceutical Secondary Standard; Certified Reference Material
2,6-Di-tert-butyl-4-methylphenol, European Pharmacopoeia (EP) Reference Standard
Supelco
Butylated hydroxyanisole, analytical standard
Sigma-Aldrich
2,6-Di-tert-butyl-4-methylphenol, tested according to Ph. Eur.
Butylhydroxyanisole, European Pharmacopoeia (EP) Reference Standard