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  • First total synthesis of the neuronal cell protecting carbazole alkaloid carbazomadurin A by sequential transition metal-catalyzed reactions.

First total synthesis of the neuronal cell protecting carbazole alkaloid carbazomadurin A by sequential transition metal-catalyzed reactions.

Chemical communications (Cambridge, England) (2003-06-05)
Hans-Joachim Knölker, Jan Knöll
RESUMEN

The highly oxygenated neuronal cell protecting carbazole alkaloid carbazomadurin A was synthesized in nine steps and 11% overall yield from isovanillic acid.

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Sigma-Aldrich
2-Bromo-6-nitrotoluene, 98%