Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.

Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.

Archives of pharmacal research (2012-05-04)

Girish Chandra, Varughese Alexander, Hyuk Woo Lee, Lak Shin Jeong

RESUMEN

An improved synthesis of DNA-dependent protein kinase inhibitor, IC86621 is described. This developed method provides an easy access to this simple molecule by using amination, acetylation and Fries rearrangement reactions.

MATERIALES

Referencia del producto

Marca

Descripción del producto

101079

Sigma-Aldrich

3-Bromophenol, 98%