Saltar al contenido
Merck

PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics.

Organic process research & development (2014-09-02)
Teppei Fujimoto, Fabian Becker, Tobias Ritter
RESUMEN

We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.

MATERIALES
Referencia del producto
Marca
Descripción del producto

Sigma-Aldrich
2-Chloro-1,3-bis(2,6-diisopropylphenyl)imidazolium chloride, ≥95%