SRP0456
BRD3 (306-417) His tag human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Sinónimos:
ORFX, RING3L, bromodomain containing 3
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
biological source
human
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
14.1 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... BRD3(8019)
General description
Human Bromodomain containing 3, also known as BRD3 or RING3L (GenBank Accession No. NM_007371) amino-acids 306 – 417 with N-terminal HIS-tag, MW = 14.1 kDa, expressed in an E. coli expression system.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Roland Gamsjaeger et al.
Molecular and cellular biology, 31(13), 2632-2640 (2011-05-11)
Recent data demonstrate that small synthetic compounds specifically targeting bromodomain proteins can modulate the expression of cancer-related or inflammatory genes. Although these studies have focused on the ability of bromodomains to recognize acetylated histones, it is increasingly becoming clear that
Janine M Lamonica et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(22), E159-E168 (2011-05-04)
Acetylation of histones triggers association with bromodomain-containing proteins that regulate diverse chromatin-related processes. Although acetylation of transcription factors has been appreciated for some time, the mechanistic consequences are less well understood. The hematopoietic transcription factor GATA1 is acetylated at conserved
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