SAB4300263

Anti-phospho-CFL1/CFL2 (pTyr⁸⁸) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CFL antibody produced in rabbit, Anti-NEM7 antibody produced in rabbit, Anti-cofilin 1 (non-muscle) / cofilin 2 (muscle) antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~19 kDa
• species reactivity: human, mouse, rat
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• isotype: IgG
• immunogen sequence: (A-T-YP-E-T)
• NCBI accession no.: NP_005498.1; NP_068733.1
• UniProt accession no.: P23528
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr88)
• Gene Information: human ... CFL1(1072) , CFL2(1073)

Descripción

Immunogen

Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T), according to the protein CFL1/CFL2.

Features and Benefits

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Target description

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable