SAB4300257

Anti-phospho-Th (pSer¹⁹) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-The antibody produced in rabbit, Anti-tyrosine hydroxylase antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 55-60 kDa
• species reactivity: human, rat
• concentration: 1 mg/mL
• technique(s): indirect immunofluorescence: 1:100-1:200
• isotype: IgG
• immunogen sequence: (A-V-SP-E-Q)
• NCBI accession no.: NP_036872.1
• UniProt accession no.: P07101
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer19)
• Gene Information: rat ... Th(25085)

Descripción

Immunogen

Peptide sequence around phosphorylation site of serine19 (A-V-S(p)-E-Q), according to the protein Th.

Features and Benefits

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Target description

The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable