SAB2501301

Anti-IDO2 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-INDOL1, indoleamine 2,3-dioxygenase 2
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: canine, bovine, human
• technique(s): indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q6ZQW0
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IDO2(169355)

Descripción

General description

Indoleamine 2,3 dioxygenase (IDO) 2 is one of the four tryptophan catabolic enzymes in mammals. IDO2 is located on human chromosome 8p21.

Immunogen

Peptide with sequence CRDKTLESILHPR, from the C-Terminus of the protein sequence according to NP_919270.2.

Biochem/physiol Actions

Indoleamine 2,3 dioxygenase (IDO) 2 plays an important role in the metabolism of tryptophan and in immune regulation. It may participate in B cell-mediated autoimmune diseases. IDO2 is required for IDO1-dependent induction of T regulatory cells (Treg). Removal of IDO2 results in attenuated contact hypersensitivity (CHS) responses.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable