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Merck
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Key Documents

07-594

Sigma-Aldrich

Anti-Histone H2A.Z Antibody

serum, Upstate®

Sinónimos:

Anti-H2A.Z-1, Anti-H2A.z, Anti-H2A/z, Anti-H2AFZ, Anti-H2AZ

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

packaging

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

UniProt accession no.

shipped in

ambient

target post-translational modification

unmodified

Gene Information

human ... H2AFZ(3015)

Specificity

Broad species cross-reactivity is expected
C-terminus of histone H2A.Z

Immunogen

peptide containing the sequence SLIGKKGQQ, corres-ponding to the C-terminus of human histone H2A.Z

Application

Detect Histone H2A.Z also known as H2AZ histone with Anti-Histone H2A.Z Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Quality

routinely evaluated by immunoblot on acid extracted proteins from HeLa cells and recombinant Histone H2A.Z (Catalog #14-597), no cross-reactivity with Histone H2A

Target description

16kDa

Physical form

0.05% sodium azide before the addition of glycerol to 30%
Serum

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Molecular cloaking of H2A.Z on mortal DNA chromosomes during nonrandom segregation.
Yang Hoon Huh,James L Sherley
Stem Cells null
H2A.Z overexpression promotes cellular proliferation of breast cancer cells.
Amy Svotelis,Nicolas Gevry,Gilles Grondin,Luc Gaudreau
Cell Cycle null
Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes.
Ontoso, D; Kauppi, L; Keeney, S; San-Segundo, PA
Chromosoma null
Chunyuan Jin et al.
Nature genetics, 41(8), 941-945 (2009-07-28)
To understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human cells. We find that a special class of NCPs
Zenab F Mchaourab et al.
Scientific data, 5, 180030-180030 (2018-03-07)
The human K562 chronic myeloid leukemia cell line has long served as an experimental paradigm for functional genomic studies. To systematically and functionally annotate the human genome, the ENCODE consortium generated hundreds of functional genomic data sets, such as chromatin

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