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Merck

UNC13B

unc-13 homolog B (C. elegans)

Sinónimos:
MUNC13, UNC13, Unc13h2
Especie:
ID UniProtKB:
ID del gen:
  • Human(10497) Summary: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
  • Mouse(22249) unc-13 homolog B (C. elegans)
  • Rat(64830) unc-13 homolog B (C. elegans)
  • Horse(100055666) unc-13 homolog B (C. elegans)
  • domestic guinea pig(100726943) unc-13 homolog B (C. elegans)
  • naked mole-rat(101717680) unc-13 homolog B (C. elegans)
  • cow(530692) unc-13 homolog B (C. elegans)
  • sheep(101117731) unc-13 homolog B (C. elegans)
  • Domestic Rabbit(100345810) unc-13 homolog B (C. elegans)
  • domestic cat(101089655) unc-13 homolog B (C. elegans)
  • dog(100683511) unc-13 homolog B (C. elegans)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-UNC13B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-UNC13B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human UNC13B,
Especie
human