UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
Sinónimos:
HLUGP4, LUGP4, UDPGT, UDPGT 1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I
Especie:
Human UGT1A9 (54600), Mouse Ugt1a9 (394434), Rat Ugt1a9 (396552), chicken UGT1A9 (771048), sheep UGT1A9 (442993), domestic guinea pig Ugt1a9 (100721353)
ID UniProtKB:
ID del gen:
- Human(54600) Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008]
- Mouse(394434) UDP glucuronosyltransferase 1 family, polypeptide A9
- Rat(396552) UDP glucuronosyltransferase 1 family, polypeptide A9
- chicken(771048) UDP glucuronosyltransferase 1 family, polypeptide A9
- sheep(442993) UDP glucuronosyltransferase 1 family, polypeptide A9
- domestic guinea pig(100721353) UDP glucuronosyltransferase 1 family, polypeptide A9
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