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Merck

TPSD1

tryptase delta 1

Sinónimos:
MCP7-LIKE, MCP7L1, MMCP-7L
Especie:
Human TPSD1 (23430), cow TPSD1 (282098)
ID UniProtKB:
Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8
ID del gen:
  • Human(23430) Summary: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008]
  • cow(282098) tryptase delta 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA040182
Anti-TPSD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
HPA049554
Anti-TPSD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Proteins

Referencia del producto
Descripción
Especie
T7063
Tryptase from human lung, buffered aqueous solution, ≥5 units/mg protein,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU127461
MISSION® esiRNA, targeting human TPSD1,
Especie
human