TP53
tumor protein p53
Sinónimos:
BCC7, LFS1, P53, TRP53
Especie:
Human TP53 (7157), Rat Tp53 (24842), Domestic Rabbit TP53 (100009292), domestic guinea pig Tp53 (100379269), sheep TP53 (443421), cow TP53 (281542), Zebrafish tp53 (30590), naked mole-rat Tp53 (101701769), dog TP53 (403869), chicken TP53 (396200) ...Más
ID UniProtKB:
ID del gen:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- sheep(443421) tumor protein p53
- cow(281542) tumor protein p53
- Zebrafish(30590) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
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ELISA
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
Anti-p53 antibody, Mouse monoclonal, clone DO-1, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Monoclonal Anti-p53 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2199, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-p53 Rabbit Monoclonal Antibody, clone RM387, affinity purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-p53 antibody, Mouse monoclonal, clone DO-7, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Cell Lines
Small Molecule - Inhibitor
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Descripción
Especie
Proteins
Referencia del producto
Descripción
Especie
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human
p53 (1-81), wild type, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human
p53 (1-363) C-terminal deletion human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Especie
human
esiRNA
Referencia del producto
Descripción
Especie