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Merck

TNFSF12

tumor necrosis factor (ligand) superfamily, member 12

Sinónimos:
APO3L, DR3LG, TWEAK
Especie:
Human TNFSF12 (8742), Mouse Tnfsf12 (21944), Rat Tnfsf12 (360548), domestic guinea pig Tnfsf12 (100713543), domestic cat TNFSF12 (101098755), Zebrafish tnfsf12 (567542), dog TNFSF12 (100568280), cow TNFSF12 (100568284), cow TNFSF12 (100551513), Domestic Rabbit TNFSF12 (100356651) ...Más
ID UniProtKB:
O43508, Q8IZK7, Q8WUZ7
ID del gen:
  • Human(8742) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
  • Mouse(21944) tumor necrosis factor (ligand) superfamily, member 12
  • Rat(360548) tumor necrosis factor ligand superfamily member 12
  • domestic guinea pig(100713543) tumor necrosis factor (ligand) superfamily, member 12
  • domestic cat(101098755) tumor necrosis factor (ligand) superfamily, member 12
  • Zebrafish(567542) tumor necrosis factor (ligand) superfamily, member 12
  • dog(100568280) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100568284) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100551513) tumor necrosis factor (ligand) superfamily, member 12
  • Domestic Rabbit(100356651) tumor necrosis factor (ligand) superfamily, member 12
  • Horse(100061872) tumor necrosis factor (ligand) superfamily, member 12
  • sheep(101122801) tumor necrosis factor (ligand) superfamily, member 12

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ELISA

Referencia del producto
Descripción
Especie
RAB0495
Mouse TWEAK ELISA Kit, for serum, plasma and cell culture supernatant,
Especie
mouse
RAB1765
Human TWEAK R ELISA, for serum, plasma and cell culture supernatants,
Especie
human
RAB0749
Human TNFSF12 ELISA Kit, ,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA004863
Anti-TNFSF13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
HPA052967
Anti-TNFSF12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB3500423
Anti-TWEAK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU227381
MISSION® esiRNA, targeting human TNFSF12,
Especie
human
EHU097141
MISSION® esiRNA, targeting human TNFSF12-TNFSF13, TNFSF13,
Especie
human