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Merck

TK2

thymidine kinase 2, mitochondrial

Sinónimos:
MTDPS2, MTTK
Especie:
ID UniProtKB:
ID del gen:
  • Human(7084) Summary: This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012]
  • Mouse(57813) thymidine kinase 2, mitochondrial
  • Rat(291824) thymidine kinase 2, mitochondrial
  • chicken(427551) thymidine kinase 2, mitochondrial
  • Zebrafish(437016) thymidine kinase 2, mitochondrial
  • naked mole-rat(101704299) thymidine kinase 2, mitochondrial
  • domestic guinea pig(100727406) thymidine kinase 2, mitochondrial
  • sheep(101103665) thymidine kinase 2, mitochondrial
  • cow(615457) thymidine kinase 2, mitochondrial
  • Horse(100065312) thymidine kinase 2, mitochondrial
  • domestic cat(101085008) thymidine kinase 2, mitochondrial
  • dog(611387) thymidine kinase 2, mitochondrial

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
3′-Deoxy-3′-fluorothymidine, 97%,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TK2,
Especie
human
MISSION® esiRNA, targeting mouse Tk2,
Especie
mouse