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Merck

SVIL

supervillin

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(6840) Summary: This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008]
  • Mouse(225115) supervillin
  • Rat(361256) supervillin
  • cow(281509) supervillin
  • dog(477965) supervillin
  • domestic cat(101098723) supervillin
  • domestic guinea pig(100729448) supervillin
  • Horse(100063045) supervillin
  • naked mole-rat(101713658) supervillin
  • chicken(420475) supervillin
  • sheep(101119493) supervillin

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Supervillin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
western blot