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Merck

SPTLC1

serine palmitoyltransferase, long chain base subunit 1

Sinónimos:
HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI
Especie:
ID UniProtKB:
ID del gen:
  • Human(10558) Summary: Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(268656) serine palmitoyltransferase, long chain base subunit 1
  • Rat(361213) serine palmitoyltransferase, long chain base subunit 1
  • sheep(101105721) serine palmitoyltransferase, long chain base subunit 1
  • dog(484192) serine palmitoyltransferase, long chain base subunit 1
  • Zebrafish(553981) serine palmitoyltransferase, long chain base subunit 1
  • naked mole-rat(101716616) serine palmitoyltransferase, long chain base subunit 1
  • chicken(426145) serine palmitoyltransferase, long chain base subunit 1
  • Domestic Rabbit(100344536) serine palmitoyltransferase, long chain base subunit 1
  • cow(614165) serine palmitoyltransferase, long chain base subunit 1
  • domestic guinea pig(100726468) serine palmitoyltransferase, long chain base subunit 1
  • domestic cat(101087947) serine palmitoyltransferase, long chain base subunit 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SPTLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-SPTLC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SPTLC1,
Especie
human