Saltar al contenido
Merck

SNX15

sorting nexin 15

Sinónimos:
HSAF001435
Especie:
ID UniProtKB:
ID del gen:
  • Human(29907) Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
  • Mouse(69024) sorting nexin 15
  • Rat(293691) sorting nexin 15
  • Zebrafish(393352) sorting nexin 15
  • cow(507751) sorting nexin 15
  • dog(612080) sorting nexin 15
  • domestic cat(101082093) sorting nexin 15
  • naked mole-rat(101702424) sorting nexin 15
  • domestic guinea pig(100724367) sorting nexin 15
  • sheep(101119948) sorting nexin 15
  • Goat(100861118) sorting nexin 15

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SNX15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
PrEST Antigen SNX15, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Snx15,
Especie
mouse