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Merck

SFTPC

surfactant protein C

Sinónimos:
BRICD6, PSP-C, SFTP2, SMDP2, SP-C
Especie:
ID UniProtKB:
ID del gen:
  • Human(6440) Summary: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
  • Mouse(20389) surfactant associated protein C
  • Rat(50683) surfactant protein C
  • domestic guinea pig(100728764) surfactant protein C
  • naked mole-rat(101713455) surfactant protein C
  • sheep(443034) surfactant protein C
  • Domestic Rabbit(100009162) surfactant protein C
  • cow(282071) surfactant protein C
  • domestic cat(101089602) surfactant protein C
  • dog(477385) surfactant protein C

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SFTPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-SFTPC Antibody, clone 3F18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SFTPC,
Especie
human