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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Sinónimos:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Especie:
Human SCN8A (6334), Mouse Scn8a (20273), Rat Scn8a (29710), chicken SCN8A (100857835), dog SCN8A (477604), Horse SCN8A (100052777), cow SCN8A (537277), naked mole-rat Scn8a (101711868), domestic guinea pig Scn8a (100734003), sheep SCN8A (101113744) ...Más
ID UniProtKB:
Q9UQD0, B9VWG8, O95788, Q9NYX2, Q9UPB2
ID del gen:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA043937
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
HPA073590
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
S0438
Anti-Sodium Channel PN4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
rat
Aplicación
western blot
S8809
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Reactividad de especies
mammals
Aplicación
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
L5647
Lidocaine hydrochloride monohydrate, solid,
Especie
human
P9879
Procaine hydrochloride, ≥97%,
Especie
human
1366013
Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1366002
Lidocaine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
SML2088
Procainamide hydrochloride, ≥98% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU187341
MISSION® esiRNA, targeting mouse Scn8a,
Especie
mouse