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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Sinónimos:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-Sodium Channel NaV1.5 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
rat
Aplicación
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Reactividad de especies
mammals
Aplicación
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Número de producto
Descripción
Especie
Flecainide acetate salt, ,
Especie
human
Flecainide acetate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Flecainide acetate, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Flecainide for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Ligand

Número de producto
Descripción
Especie
Lamotrigine, ≥98%, powder,
Especie
rat, human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human SCN5A,
Especie
human