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Merck

RUNX3

runt-related transcription factor 3

Sinónimos:
AML2, CBFA3, PEBP2aC
Especie:
ID UniProtKB:
ID del gen:
  • Human(864) Summary: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12399) runt related transcription factor 3
  • Rat(156726) runt-related transcription factor 3
  • chicken(769687) runt-related transcription factor 3
  • Zebrafish(58127) runt-related transcription factor 3
  • naked mole-rat(101726268) runt-related transcription factor 3
  • cow(617389) runt-related transcription factor 3
  • dog(487366) runt-related transcription factor 3
  • domestic cat(101080466) runt-related transcription factor 3
  • sheep(101119625) runt-related transcription factor 3
  • Horse(100071400) runt-related transcription factor 3
  • domestic guinea pig(100735006) runt-related transcription factor 3

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-RUNX3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse RUNX3,
Especie
mouse
MISSION® esiRNA, targeting human RUNX3,
Especie
human