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Merck

PVRL1

poliovirus receptor-related 1 (herpesvirus entry mediator C)

Sinónimos:
CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(5818) Summary: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
  • Mouse(58235) poliovirus receptor-related 1
  • Rat(192183) poliovirus receptor-related 1
  • dog(489363) poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • domestic cat(101098252) poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • domestic guinea pig(100724766) poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • naked mole-rat(101713982) poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • cow(533492) poliovirus receptor-related 1 (herpesvirus entry mediator C)
  • sheep(101116172) poliovirus receptor-related 1 (herpesvirus entry mediator C)

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ELISA

Referencia del producto
Descripción
Especie
Human Nectin-1 ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-NECTIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NECTIN1,
Especie
human
MISSION® esiRNA, targeting mouse Pvrl1,
Especie
mouse