PTPRJ
protein tyrosine phosphatase, receptor type, J
Sinónimos:
CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
Especie:
Human PTPRJ (5795), Mouse Ptprj (19271), Rat Ptprj (29645), chicken PTPRJ (395330), Domestic Rabbit PTPRJ (100347798), domestic cat PTPRJ (101086598), dog PTPRJ (483617), Horse PTPRJ (100058689), cow PTPRJ (508150), sheep PTPRJ (101121292) ...Más
ID UniProtKB:
ID del gen:
- Human(5795) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19271) protein tyrosine phosphatase, receptor type, J
- Rat(29645) protein tyrosine phosphatase, receptor type, J
- chicken(395330) protein tyrosine phosphatase, receptor type, J
- Domestic Rabbit(100347798) protein tyrosine phosphatase, receptor type, J
- domestic cat(101086598) protein tyrosine phosphatase, receptor type, J
- dog(483617) protein tyrosine phosphatase, receptor type, J
- Horse(100058689) protein tyrosine phosphatase, receptor type, J
- cow(508150) protein tyrosine phosphatase, receptor type, J
- sheep(101121292) protein tyrosine phosphatase, receptor type, J
- domestic guinea pig(100729887) protein tyrosine phosphatase, receptor type, J
- naked mole-rat(101726039) protein tyrosine phosphatase, receptor type, J
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ELISA
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Antibodies
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Aplicación
Anti-PTPRJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Proteins
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